Lisa Miller

Biophysical Chemist

Lisa Miller is the manager of the User Services, Communications, Education, and Outreach (USCEO) Office at the National Synchrotron Light Source II at Brookhaven National Laboratory.

Lisa Miller's research focuses on the study of the chemical makeup of cells and tissues using synchrotron-based infrared and x-ray imaging. Her work has three primary research areas: (1) understanding how the nanostructure and chemical composition of bone affect its mechanical properties in osteoarthritis and osteoporosis, (2) elucidating the role of metal ions in protein misfolding and neurodegeneration in Alzheimer's disease and Cerebral Amyloid Angiopathy, and (3) optimizing nutrient availability in the rhizosphere of plants for improved biomass production.

Professional Activities

Phone: 344-2091


  • Ph.D. 1995: Biophysics, Albert Einstein College of Medicine
  • M.S. 1992: Chemistry, Georgetown University
  • B.S. 1989: Chemistry, John Carroll University


Key Publications

  • "A Acerbo, G Carr, S Judex, L Miller Imaging the Material Properties of Bone Specimens Using Reflection-Based Infrared Microspectroscopy. Anal. Chem., 84(8), 3607-3613 (2012)."
  • "A Leskovjan, A Kretlow, A Lanzirotti, R Barrea, S Vogt, L Miller Increased Brain Iron Coincides with Early Plaque Formation in a Mouse Model of Alzheimer's Disease. NeuroImage, 55, 32-38 (2011)."
  • "T Victor, N Depratt, S Cseke, L Miller, L James Cseke Imaging Nutrient Distribution in the Rhizosphere Using FTIR Imaging. Anal. Chem., 89(9), 4831-4837 (2017). [doi: 10.1021/acs.analchem.6b04376]"
  • "P Gelfand, R Smith, E Stavitski, D Borchelt, L Miller Characterization of Protein Structural Changes in Living Cells Using Time-Lapsed FTIR Imaging. Anal. Chem., 87(12), 6025-6021 (2015)."
  • "E Stavitski, R Smith, M Bourassa, A Acerbo, G Carr, L Miller Dynamic Full-Field Infrared Imaging with Multiple Synchrotron Beams. Anal. Chem., 85(7), 3599-3605 (2013)."

All Publications